Principal Scientist - Inflammation Biomarkers

Company: Amgen
Location: Washington
Posted on: January 19, 2026

Job Description:

Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Principal Scientist - Inflammation Biomarkers What you will do Lets do this. Lets change the world. In this vital role you will help drive scientific and technical plans collaboratively with other members of the Precision Medicine function, as well as with members of the Amgen research and development community. You will successfully partner with cross-functional stakeholders to drive clinical biomarker innovation for clinical-stage assets in inflammatory diseases. The Principal Scientist will possess biomarker expertise in inflammatory and/or rare diseases such as arthritis, atopic dermatitis, inflammatory bowel disease, lupus, asthma, and/or autoimmune endocrinopathies. Key Responsibilities: Preparing clinical biomarker strategies, leading biomarker development, implementation, and execution for one or more programs Responsible for biomarker elements in clinical protocols, biomarker analysis plans, regulatory submissions, investigator meetings, advisory boards and publications Build productive relationships with team members and functional groups for integrating an aligned and prioritized clinical biomarker evidence plan that addresses clinical objectives and translational research Partner with cross-functional stakeholders including to drive biomarker innovation at product level Establish and implement biomarker studies and collaborations with academic laboratories/KOLs Interpret and communicate key clinical biomarker findings to cross-functional teams including Precision Medicine teams and leadership Responsible for robust clinical biomarker plans to deliver patient stratification/selection, pharmacodynamics, mechanism of action and resistance evidence from clinical trial samples What we expect of you We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications. Basic Qualifications: Doctorate degree in a bioscience or medical discipline and 2 years of industry experience Or Masters degree in a bioscience or medical discipline and 4 years of industry experience Or Bachelors degree in a bioscience or medical discipline and 6 years of industry experience Or Associates degree in a bioscience or medical discipline and 10 years of industry experience Or High school diploma / GED and 12 years of directly related industry experience Preferred Qualifications: PhD with 3 or more years pharmaceutical industry experience, developing biomarker strategies in a clinical development setting and/or in preclinical biomarker discovery/validation Knowledge and translational biomarker experience in inflammation is highly desirable Strong background in immunology, cell biology and genomics Clinical development experience working with cross-functional teams conducting clinical trials Experience in developing program-based strategies for pharmacodynamic, predictive, and exploratory biomarkers Experience implementing a broad array of biomarker platforms and technologies to support clinical-stage programs Demonstrated ability to establish and implement biomarker studies and collaborations with academic laboratories/KOLs Experience in assay development and qualification and analysis of clinical samples Experience managing biomarker assay outsourcing processes with external vendors and CROs Poise and professionalism with strong communication and influencing skills in a dynamic environment What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Keywords: Amgen, Columbia , Principal Scientist - Inflammation Biomarkers, Science, Research & Development , Washington, Maryland